Use Finasteride/Dutasteride + Oral Minoxidil for regrowth while ignoring low-ROI serums and shampoos.
Evidence Gallery
In Depth Protocol
The Root Cause: Male Pattern Baldness (MPB) is not caused by "poor blood flow" or "clogged pores." It is caused by Dihydrotestosterone (DHT) shrinking the hair follicle (Miniaturization) until it dies.
5-AR Inhibitors: You must block the enzyme 5-Alpha Reductase (5-AR) that converts Testosterone into DHT:
Finasteride: Inhibits Type II 5-AR. Reduces Serum DHT by ~73% and Scalp DHT by ~41%. It has a short half-life (~6 hours).
Dutasteride: Much stronger; inhibits both Type I & II. Reduces Serum DHT by >90% and Scalp DHT by ~51%. It has a long half-life (5 weeks).
The Regrowth:Oral Minoxidil is a vasodilator. At low doses (1.25mg – 2.5mg), it has a 90% response rate for regrowing hair with minimal side effects (only 4.8%), though low blood pressure is a possible risk.
The Placebo Trap: Treatments like Biotin, Caffeine Shampoos, PRP, and "Scalp Massages" are effectively placebos compared to 5-AR inhibitors and offer a terrible ROI.
âś… Pros
High ROI: Oral medication (Fin/Min) have high Effectiveness and potency
Free Testosterone: Serum Blood testosterone increase of up to 10-23%
Ask a Medical Profesional
⚠️ Cons
Dutasteride: Beware of extremely high half life of 5 weeks. Start Dutas gradually
Libido(Hormonal): Finasteride/Dutasteride can cause libido reduction or erectile dysfunction in ~1-2% of users.
Minoxidil: Low blood pressure, palpitations and Hair Growth Everywhere (Hyperthrichosis)